Title : Expanding the role of vasopressin antagonism in polycystic kidney diseases: From adults to children?

Pub. Date : 2018 Mar

PMID : 28455745






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The vasopressin V2 receptor (V2R) antagonist tolvaptan lowers cAMP in cystic tissues and slows renal cystic progression and kidney function decline when given over 3 years in adult ADPKD patients. Tolvaptan arginine vasopressin receptor 2 Homo sapiens
2 The vasopressin V2 receptor (V2R) antagonist tolvaptan lowers cAMP in cystic tissues and slows renal cystic progression and kidney function decline when given over 3 years in adult ADPKD patients. Tolvaptan arginine vasopressin receptor 2 Homo sapiens