Title : GDF11 Attenuates Development of Type 2 Diabetes via Improvement of Islet β-Cell Function and Survival.

Pub. Date : 2017 Jul

PMID : 28450417






1 Functional Relationships(s)
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1 Mechanistically, the GDF11-mediated protective effects could be attributed to the activation of transforming growth factor-beta/Smad2 and phosphatidylinositol-4,5-bisphosphate 3-kinase-AKT-FoxO1 signaling. Phosphatidylinositol 4,5-Diphosphate thymoma viral proto-oncogene 1 Mus musculus