Title : Release of tumor necrosis factor-alpha from macrophages. Enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides.

Pub. Date : 1988 Oct 1

PMID : 2844899






1 Functional Relationships(s)
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1 In contrast, agents increasing intracellular cAMP concentrations such as PGE1, higher PGE2 doses, isoproterenol, and theophylline, all suppressed TNF-alpha synthesis. Theophylline tumor necrosis factor Rattus norvegicus