Pub. Date : 2017 Aug
PMID : 28448946
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS: The kavalactone methysticin was administered once a week for a period of 6 months to 6 month old transgenic APP/Psen1 mice by oral gavage. | methysticin | presenilin 1 | Mus musculus |
| 2 | The Abeta deposition in brains of methysticin-treated APP/Psen1 mice was not altered compared to untreated mice. | methysticin | presenilin 1 | Mus musculus |
| 3 | In addition, the oxidative damage of hippocampi from APP/Psen1 mice was reduced by methysticin treatment. | methysticin | presenilin 1 | Mus musculus |
| 4 | Most importantly, methysticin treatment significantly attenuated the long-term memory decline of APP/Psen1 mice. | methysticin | presenilin 1 | Mus musculus |