Pub. Date : 2017 May 4
PMID : 28445460
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nine neurodegenerative diseases are caused by expanded polyglutamine (polyQ) tracts in different proteins, such as huntingtin in Huntington"s disease and ataxin 3 in spinocerebellar ataxia type 3 (SCA3). | polyglutamine | ataxin 3 | Mus musculus |
| 2 | Nine neurodegenerative diseases are caused by expanded polyglutamine (polyQ) tracts in different proteins, such as huntingtin in Huntington"s disease and ataxin 3 in spinocerebellar ataxia type 3 (SCA3). | polyglutamine | ataxin 3 | Mus musculus |
| 3 | Nine neurodegenerative diseases are caused by expanded polyglutamine (polyQ) tracts in different proteins, such as huntingtin in Huntington"s disease and ataxin 3 in spinocerebellar ataxia type 3 (SCA3). | polyglutamine | ataxin 3 | Mus musculus |
| 4 | Nine neurodegenerative diseases are caused by expanded polyglutamine (polyQ) tracts in different proteins, such as huntingtin in Huntington"s disease and ataxin 3 in spinocerebellar ataxia type 3 (SCA3). | polyglutamine | ataxin 3 | Mus musculus |
| 5 | Nine neurodegenerative diseases are caused by expanded polyglutamine (polyQ) tracts in different proteins, such as huntingtin in Huntington"s disease and ataxin 3 in spinocerebellar ataxia type 3 (SCA3). | polyglutamine | ataxin 3 | Mus musculus |
| 6 | Nine neurodegenerative diseases are caused by expanded polyglutamine (polyQ) tracts in different proteins, such as huntingtin in Huntington"s disease and ataxin 3 in spinocerebellar ataxia type 3 (SCA3). | polyglutamine | ataxin 3 | Mus musculus |
| 7 | Here we show that the polyQ domain enables wild-type ataxin 3 to interact with beclin 1, a key initiator of autophagy. | polyglutamine | ataxin 3 | Mus musculus |
| 8 | This activity of ataxin 3 and its polyQ-mediated interaction with beclin 1 was competed for by other soluble proteins with polyQ tracts in a length-dependent fashion. | polyglutamine | ataxin 3 | Mus musculus |
| 9 | This activity of ataxin 3 and its polyQ-mediated interaction with beclin 1 was competed for by other soluble proteins with polyQ tracts in a length-dependent fashion. | polyglutamine | ataxin 3 | Mus musculus |