Title : The role of interleukin-1β and extracellular signal-regulated kinase 1/2 in glucose-stimulated insulin secretion.

Pub. Date : 2017 May

PMID : 28433068






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The role of interleukin-1beta and extracellular signal-regulated kinase 1/2 in glucose-stimulated insulin secretion. Glucose mitogen-activated protein kinase 3 Mus musculus
2 Compared with the 0mM glucose group, the level of ERK1/2 phosphorylation was increased in the 1.38mM and 5.5mM glucose groups. Glucose mitogen-activated protein kinase 3 Mus musculus
3 Compared with the 0mM glucose group, the level of ERK1/2 phosphorylation was increased in the 1.38mM and 5.5mM glucose groups. Glucose mitogen-activated protein kinase 3 Mus musculus
4 After intervention by 0.15 ng/mL, 1.5 ng/mL, and 15 ng/mL IL-1beta, the level of ERK1/2 phosphorylation induced by 1.38mM glucose stimulation decreased in a dose-dependent manner, and the insulin level correspondingly decreased. Glucose mitogen-activated protein kinase 3 Mus musculus