Title : Candesartan, an Insurmountable Antagonist of Angiotensin II-mediated Contractile Effects in Isolated Vascular Preparations: Comparison with Irbesartan, Losartan and its Active Metabolite (EXP-3174).

Pub. Date : 2000

PMID : 28425810






2 Functional Relationships(s)
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1 Both irbesartan and EXP-3174, the active metabolite of losartan, have also previously been described in some studies as insurmountable AT 1 -receptor blockers, whereas losartan exhibits surmountable blockade of the AT 1 -receptor. losartan carboxylic acid angiotensin II receptor, type 1a Rattus norvegicus
2 Both irbesartan and EXP-3174, the active metabolite of losartan, have also previously been described in some studies as insurmountable AT 1 -receptor blockers, whereas losartan exhibits surmountable blockade of the AT 1 -receptor. losartan carboxylic acid angiotensin II receptor, type 1a Rattus norvegicus