Title : Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils.

Pub. Date : 1988 Aug

PMID : 2841359






1 Functional Relationships(s)
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1 Human neutrophils, when stimulated with phorbol myristate acetate or fMet-Leu-Phe in the presence or absence of cytochalasin B, released metalloproteinases that catalytically inactivated the plasma serine proteinase inhibitor, alpha 1-antitrypsin. Tetradecanoylphorbol Acetate serpin family A member 1 Homo sapiens