Title : High expression of P2X7R is an independent postoperative indicator of poor prognosis in colorectal cancer.

Pub. Date : 2017 Jun

PMID : 28412208






2 Functional Relationships(s)
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1 Treatment with P2X7R agonist BzATP led to the activation of Akt and NF-kappaB pathways. 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate AKT serine/threonine kinase 1 Homo sapiens
2 Consequently, we revealed that BzATP accelerated the proliferation of CRC cells, whereas co-incubation with PI3K/Akt inhibitor LY294002 significantly impaired BzATP-induced proliferation of CRC cells. 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate AKT serine/threonine kinase 1 Homo sapiens