Title : The inhibition of arachidonic acid mobilization in human platelets by R59 022, a diacylglycerol kinase inhibitor.

Pub. Date : 1988 Aug 12

PMID : 2840967






2 Functional Relationships(s)
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1 In the present study, we have investigated the effects of this drug on arachidonic acid mobilization occurring in response to thrombin in intact human platelets. Arachidonic Acid coagulation factor II, thrombin Homo sapiens
2 We conclude that the observed inhibition of thrombin-induced arachidonic acid mobilization by R59 022 may be due to its effects on the activities of diacylglycerol lipase/phospholipase A2. Arachidonic Acid coagulation factor II, thrombin Homo sapiens