Title : Mammalian ALOX15 orthologs exhibit pronounced dual positional specificity with docosahexaenoic acid.

Pub. Date : 2017 Jul

PMID : 28400162






2 Functional Relationships(s)
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1 Here we expressed the ALOX15 orthologs of eight different mammalian species as well as human ALOX12 and ALOX15B as recombinant his-tag fusion proteins and characterized their reaction specificity with the most abundantly occurring polyunsaturated fatty acids (PUFAs) including 5,8,11,14,17-eicosapentaenoic acid (EPA) and 4,7,10,13,16,19-docosahexaenoic acid (DHA). Fatty Acids, Unsaturated arachidonate 15-lipoxygenase Homo sapiens
2 Here we expressed the ALOX15 orthologs of eight different mammalian species as well as human ALOX12 and ALOX15B as recombinant his-tag fusion proteins and characterized their reaction specificity with the most abundantly occurring polyunsaturated fatty acids (PUFAs) including 5,8,11,14,17-eicosapentaenoic acid (EPA) and 4,7,10,13,16,19-docosahexaenoic acid (DHA). Fatty Acids, Unsaturated arachidonate 15-lipoxygenase Homo sapiens