Pub. Date : 2017 Jun
PMID : 28399721
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | INTRODUCTION: Prostacyclin is produced in vascular endothelial cells and acts via the IP prostacyclin receptor to cause vasodilation and inhibit smooth muscle cell proliferation and platelet aggregation. | Epoprostenol | prostaglandin I2 receptor | Homo sapiens |
| 2 | The newest agent targeting the prostacyclin pathway, the selective prostacyclin receptor agonist selexipag, is administered orally, and has been shown to reduce a composite morbidity/mortality endpoint. | Epoprostenol | prostaglandin I2 receptor | Homo sapiens |