Title : MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

Pub. Date : 2017 Jun 20

PMID : 28398509






3 Functional Relationships(s)
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1 Further, MLL4 and CBP identify super-enhancers (SEs) of adipogenesis and that MLL3/MLL4 are required for SE formation. ses lysine (K)-specific methyltransferase 2D Mus musculus
2 Finally, in brown adipocytes differentiated in culture, MLL4 identifies primed SEs of genes fully activated in BAT such as Ucp1. ses lysine (K)-specific methyltransferase 2D Mus musculus
3 Comparison of MLL4-defined SEs in brown and white adipogenesis identifies brown-specific SE-associated genes that could be involved in BAT functions. ses lysine (K)-specific methyltransferase 2D Mus musculus