Pub. Date : 2017 Apr 11
PMID : 28397817
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. | Tenofovir | succinate dehydrogenase complex iron sulfur subunit B | Homo sapiens |
| 2 | Analysis of the proteins in TCA cycle showed succinate dehydrogenase subunit B (SDHB) was nearly depleted in glucose oxidative phosphorylation pathway however certain enzymes in the glycolysis and glycogen synthesis pathway had elevated expression in TFV and ADV-treated HK-2 cells. | Tenofovir | succinate dehydrogenase complex iron sulfur subunit B | Homo sapiens |
| 3 | Analysis of the proteins in TCA cycle showed succinate dehydrogenase subunit B (SDHB) was nearly depleted in glucose oxidative phosphorylation pathway however certain enzymes in the glycolysis and glycogen synthesis pathway had elevated expression in TFV and ADV-treated HK-2 cells. | Tenofovir | succinate dehydrogenase complex iron sulfur subunit B | Homo sapiens |