Title : Enhanced in vitro growth suppression of human glioblastoma cultures treated with the combination of recombinant fibroblast and immune interferons.

Pub. Date : 1988 May-Jun

PMID : 2839097






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 IFN-beta ser induced a greater than or equal to 50% reduction in the 7 day growth of 6 of the 15 cultures. Serine interferon beta 1 Homo sapiens
2 In contrast, when treated with the combination of IFN-beta ser plus IFN-gamma, 1000 Units/ml of each interferon preparation, 12 of 15 cultures were inhibited by greater than or equal to 50% after 7 days growth. Serine interferon beta 1 Homo sapiens
3 One glioblastoma culture, G-7, was studied through 45 passages and displayed the same sensitivity at different passages to growth inhibition when exposed to IFN-beta ser, IFN-gamma or both interferons. Serine interferon beta 1 Homo sapiens