Title : Cucurbitacin B Protects Against Pressure Overload Induced Cardiac Hypertrophy.

Pub. Date : 2017 Nov

PMID : 28390176






1 Functional Relationships(s)
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1 The Cucurbitacin B-mediated mitigated cardiac hypertrophy was attributable to the increasing level of autophagy, which was associated with the blockade of Akt/mTOR/FoxO3a signal pathway, validated by SC79, MK2206, and 3-MA, the Akt agonist, inhibitor and autophagy inhibitor in vitro. 3-methyladenine thymoma viral proto-oncogene 1 Mus musculus