Title : Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity.

Pub. Date : 2017 Jul 1

PMID : 28387831






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cytosine deaminase in infected tumor cells converts the antifungal prodrug 5-fluorocytosine into the anticancer drug 5-fluorouracil, mediating local tumor destruction without significant systemic adverse effects. Flucytosine cytosine deaminase Saccharomyces cerevisiae S288C