Pub. Date : 2017 Nov
PMID : 28380657
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Genetic Polymorphisms in Organic Cation Transporter 1 Attenuates Hepatic Metformin Exposure in Humans. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 2 | The aim of this study was to examine if common polymorphisms in SLC22A1, encoding the transporter protein OCT1, affect the hepatic distribution of metformin in humans. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 3 | The aim of this study was to examine if common polymorphisms in SLC22A1, encoding the transporter protein OCT1, affect the hepatic distribution of metformin in humans. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 4 | Hepatic distribution of metformin was significantly reduced after oral intake in carriers of M420del and R61C variants in SLC22A1 without being associated with changes in circulating levels of metformin. | Metformin | solute carrier family 22 member 1 | Homo sapiens |