Pub. Date : 2017
PMID : 28377719
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, prolonged GTN treatment induces tolerance, largely due to increased oxidative stress and reduced aldehyde dehydrogenase-2 (ALDH-2) expression. | Nitroglycerin | aldehyde dehydrogenase 1 family, member A1 | Rattus norvegicus |
| 2 | However, prolonged GTN treatment induces tolerance, largely due to increased oxidative stress and reduced aldehyde dehydrogenase-2 (ALDH-2) expression. | Nitroglycerin | aldehyde dehydrogenase 1 family, member A1 | Rattus norvegicus |
| 3 | GTN+placebo infusion significantly increased superoxide levels, decreased ALDH-2 and attenuated GTN-mediated vascular relaxation. | Nitroglycerin | aldehyde dehydrogenase 1 family, member A1 | Rattus norvegicus |
| 4 | Serelaxin co-treatment with GTN significantly enhanced GTN-mediated vascular relaxation, reduced superoxide levels and increased ALDH-2 expression compared to GTN+placebo-treated rats. | Nitroglycerin | aldehyde dehydrogenase 1 family, member A1 | Rattus norvegicus |
| 5 | Conclusion: Our data demonstrate that a combination of serelaxin treatment with low dose GTN attenuates the development of GTN-induced tolerance by reducing superoxide production and increasing ALDH-2 expression in the rat aorta. | Nitroglycerin | aldehyde dehydrogenase 1 family, member A1 | Rattus norvegicus |
| 6 | Conclusion: Our data demonstrate that a combination of serelaxin treatment with low dose GTN attenuates the development of GTN-induced tolerance by reducing superoxide production and increasing ALDH-2 expression in the rat aorta. | Nitroglycerin | aldehyde dehydrogenase 1 family, member A1 | Rattus norvegicus |