Title : Effect of Long-term In Vitro Lithium Exposure on mRNA Levels of Claudin-3, CYP1A1, ABCG2 and GSTM3 Genes in the hCMEC/D3 Human Brain Endothelial Cell Line.

Pub. Date : 2017 Dec

PMID : 28367588






2 Functional Relationships(s)
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1 BACKGROUND AND OBJECTIVES: Lithium chloride (LiCl) has been shown to improve the tightness of brain endothelial cell monolayers in vitro by inhibition of the GSK-3beta enzyme, activation of the Wnt/beta-catenin pathway and regulation of tight junction (TJ) protein expression. Lithium Chloride glycogen synthase kinase 3 beta Homo sapiens
2 BACKGROUND AND OBJECTIVES: Lithium chloride (LiCl) has been shown to improve the tightness of brain endothelial cell monolayers in vitro by inhibition of the GSK-3beta enzyme, activation of the Wnt/beta-catenin pathway and regulation of tight junction (TJ) protein expression. Lithium Chloride glycogen synthase kinase 3 beta Homo sapiens