Title : Evidence for human liver mediated free-radical formation by doxorubicin and mitozantrone.

Pub. Date : 1985 Oct

PMID : 2835961






1 Functional Relationships(s)
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1 studies showed the presence of doxorubicin (g = 2.0038) and mitozantrone (g = 2.0036) free radicals in human liver microsomes incubated with drug (50 microD) and supplemented with NADPH. Free Radicals 2,4-dienoyl-CoA reductase 1 Homo sapiens