Pub. Date : 2017 Jun
PMID : 28351683
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Acid hydrolysis of both compounds yielded oleanolic acid (3) which was non or least toxic to human peripheral blood mono nuclear cells (Selectivity index = >10) while retaining similar macrofilaricidal (IC50 = 38.4 muM) and microfilaricidal (IC50 = 35.6 muM) activities. | Oleanolic Acid | latexin | Homo sapiens |
2 | Acid hydrolysis of both compounds yielded oleanolic acid (3) which was non or least toxic to human peripheral blood mono nuclear cells (Selectivity index = >10) while retaining similar macrofilaricidal (IC50 = 38.4 muM) and microfilaricidal (IC50 = 35.6 muM) activities. | Oleanolic Acid | latexin | Homo sapiens |
3 | In adult female worms treated with 50 and 100 muM doses of oleanolic acid, condensation of nuclear DNA, apoptotic body formation and tissue damage was observed by using Hoechst 33342 staining, TUNEL assay and Hematoxylin and Eosin staining respectively. | Oleanolic Acid | latexin | Homo sapiens |