Title : Rapid and Reliable Genotyping of HLA-B*57:01 in Four Chinese Populations Using a Single-Tube Duplex Real-Time Polymerase Chain Reaction Assay.

Pub. Date : 2017 Jul

PMID : 28346841






2 Functional Relationships(s)
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1 HLA-B*57:01 is strongly associated with severe adverse drug reaction induced by the anti-HIV drug abacavir (ABC) and antibiotic flucloxacillin. Floxacillin major histocompatibility complex, class I, B Homo sapiens
2 The newly established real-time PCR assay provides a rapid and reliable tool for HLA-B*57:01 allele screening before the prescription of ABC and flucloxacillin in clinical practice. Floxacillin major histocompatibility complex, class I, B Homo sapiens