Title : NLRP3 inflammasome: Its regulation and involvement in atherosclerosis.

Pub. Date : 2018 Mar

PMID : 28345767






1 Functional Relationships(s)
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1 Modern hypotheses introduce atherosclerosis as an inflammatory/lipid-based disease and NLRP3 inflammasome has been considered as a link between lipid metabolism and inflammation because crystalline cholesterol and oxidized low-density lipoprotein (oxLDL) (two abundant components in atherosclerotic plaques) activate NLRP3 inflammasome. Cholesterol NLR family pyrin domain containing 3 Homo sapiens