Pub. Date : 1988 May
PMID : 2834186
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using a clonal strain of cultured Leydig tumor cells (designated MA-10), we have examined the effects of Ca+2 on the activation of cAMP accumulation and steroid biosynthesis by hCG. | Steroids | hypertrichosis 2 (generalised, congenital) | Homo sapiens |
| 2 | We conclude that Ca+2 is an inhibitor of the hCG-activated adenylate cyclase in Leydig tumor cells, and that this inhibition imposes a limitation on the ability of hCG to activate steroid biosynthesis. | Steroids | hypertrichosis 2 (generalised, congenital) | Homo sapiens |