Title : Role of transient receptor potential vanilloid 1 in the modulation of airway smooth muscle tone and calcium handling.

Pub. Date : 2017 Jun 1

PMID : 28336810






1 Functional Relationships(s)
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1 In guinea pig tracheal ring organ bath experiments, the TRPV1 agonist capsaicin led to ASM contraction, but this contraction was significantly attenuated by the sodium channel inhibitor bupivacaine (n = 4, P < 0.05) and the neurokinin-2 receptor antagonist GR-159897 (n = 4, P < 0.05), suggesting that this contraction is neutrally mediated. Capsaicin transient receptor potential cation channel subfamily V member 1 Cavia porcellus