Title : Simultaneous blockade of NMDA receptors and PARP-1 activity synergistically alleviate immunoexcitotoxicity and bioenergetics in 3-nitropropionic acid intoxicated mice: Evidences from memantine and 3-aminobenzamide interventions.

Pub. Date : 2017 May 15

PMID : 28322842






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Simultaneous blockade of NMDA receptors and PARP-1 activity synergistically alleviate immunoexcitotoxicity and bioenergetics in 3-nitropropionic acid intoxicated mice: Evidences from memantine and 3-aminobenzamide interventions. Memantine poly (ADP-ribose) polymerase family, member 1 Mus musculus
2 Present study was designed to determine whether the combination of memantine (MN) and 3-aminobenzamide (3-AB), PARP inhibitor, can ameliorate immunoexcitotoxicity and improve bioenergetics in a better manner than individual administration against 3-NP intoxication in mice. Memantine poly (ADP-ribose) polymerase family, member 1 Mus musculus