Pub. Date : 2017 Mar 21
PMID : 28322340
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | H2O2/Zn2+ induced concentration-dependent increases in cytosolic Ca2+ concentration ([Ca2+]c), which was inhibited by PJ34, a PARP inhibitor, and abolished by TRPM2 knockout (TRPM2-KO). | Hydrogen Peroxide | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 2 | Pathological concentrations of H2O2/Zn2+ induced substantial cell death that was inhibited by PJ34 and DPQ, PARP inhibitors, 2-APB, a TRPM2 channel inhibitor, and prevented by TRPM2-KO. | Hydrogen Peroxide | poly(ADP-ribose) polymerase 1 | Homo sapiens |