Title : Synthesis and antiplasmodial activity of novel indoleamide derivatives bearing sulfonamide and triazole pharmacophores.

Pub. Date : 2017 May 5

PMID : 28319782






1 Functional Relationships(s)
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Protein Name
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1 Among all the indoleamides, compounds 22, 24, 26 and 30 with sulfonamide pharmacophore showed promising activity with IC50 of 1.87, 1.93, 2.00, 2.17 muM against CQ sensitive Pf3D7 strain and 1.69, 2.12, 1.60, 2.19 muM against CQ resistant PfK1 strain, respectively. Sulfonamides latexin Homo sapiens