Title : [Mechanism of angiotensin-converting enzyme 2 overexpression improving collagen synthesis in lung].

Pub. Date : 2017 Mar 14

PMID : 28316159






2 Functional Relationships(s)
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1 Wild type and ACE2 over-expressing mice were instilled with bleomycin endotracheally (3.5 mg/kg) or the same volume saline. Bleomycin angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus
2 In bleomycin induced lung fibrosis in mice, ACE2(+ /+) -BLM mice exhibited milder lung fibrosis and lower NOX4 protein level but higher LC3-IIprotein level compared with WT-BLM mice. Bleomycin angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus