Title : A role for Gi in control of thrombin receptor-phospholipase C coupling in human platelets.

Pub. Date : 1988 Mar 5

PMID : 2830284






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Epinephrine added following thrombin desensitization restored both the ability of thrombin to release Ca2+ stores and stimulate inositol phospholipid hydrolysis. Epinephrine coagulation factor II, thrombin Homo sapiens
2 Epinephrine added following thrombin desensitization restored both the ability of thrombin to release Ca2+ stores and stimulate inositol phospholipid hydrolysis. Epinephrine coagulation factor II, thrombin Homo sapiens
3 Pretreatment of platelets with phorbol dibutyrate at concentrations which specifically activate protein kinase C increased the rate of desensitization of the thrombin-induced release of Ca2+ stores and abolished the ability of epinephrine to restore the thrombin response. Epinephrine coagulation factor II, thrombin Homo sapiens
4 Pretreatment of platelets with phorbol dibutyrate at concentrations which specifically activate protein kinase C increased the rate of desensitization of the thrombin-induced release of Ca2+ stores and abolished the ability of epinephrine to restore the thrombin response. Epinephrine coagulation factor II, thrombin Homo sapiens
5 This protein is involved in thrombin stimulation of phospholipase C but is not directly stimulatory since epinephrine alone does not activate this enzyme. Epinephrine coagulation factor II, thrombin Homo sapiens