Pub. Date : 1987 Dec 15
PMID : 2829843
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Reconstitution of the receptor kinase into leaky vesicles containing phosphatidylcholine and phosphatidylethanolamine (1:1, w/w) by detergent removal on Sephadex G-50 results in the complete loss of receptor kinase sensitivity to activation by insulin. | Phosphatidylcholines | insulin | Homo sapiens |
2 | These data indicate that the phospholipid environment of insulin receptors can modulate its binding and kinase activity, and phosphatidylserine acts to restore insulin-sensitivity to the receptor kinase incorporated into phosphatidylcholine/phosphatidylethanolamine vesicles. | Phosphatidylcholines | insulin | Homo sapiens |
3 | These data indicate that the phospholipid environment of insulin receptors can modulate its binding and kinase activity, and phosphatidylserine acts to restore insulin-sensitivity to the receptor kinase incorporated into phosphatidylcholine/phosphatidylethanolamine vesicles. | Phosphatidylcholines | insulin | Homo sapiens |