Pub. Date : 2018 Jan
PMID : 28295305
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT1 R upregulation are required for doxorubicin-induced cardiotoxicity. | Doxorubicin | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | We found that MAPK signaling pathways, especially ERK1/2, participated in modulating AT1 R gene expression through DOX-induced mitochondrial ROS release. | Doxorubicin | mitogen-activated protein kinase 3 | Homo sapiens |
| 3 | We found that MAPK signaling pathways, especially ERK1/2, participated in modulating AT1 R gene expression through DOX-induced mitochondrial ROS release. | Doxorubicin | mitogen-activated protein kinase 3 | Homo sapiens |