Pub. Date : 2017 May
PMID : 28284718
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Proliferation of Ba/F3 cells transduced with novel JAK3 mutations (JAK3H583Y and JAK3G589D) was independent of IL-3 and was inhibited by the JAK3 inhibitor tofacitinib (means +- SD drug concentration causing a 50% inhibition of the desired activity, 85 +- 10 nmol/L and 54 +- 9 nmol/L). | tofacitinib | Janus kinase 3 | Mus musculus |
| 2 | Proliferation of Ba/F3 cells transduced with novel JAK3 mutations (JAK3H583Y and JAK3G589D) was independent of IL-3 and was inhibited by the JAK3 inhibitor tofacitinib (means +- SD drug concentration causing a 50% inhibition of the desired activity, 85 +- 10 nmol/L and 54 +- 9 nmol/L). | tofacitinib | Janus kinase 3 | Mus musculus |