Title : Protective effect of medicinal fungus Xylaria nigripes mycelia extracts against hydrogen peroxide-induced apoptosis in PC12 cells.

Pub. Date : 2017 Mar

PMID : 28281874






1 Functional Relationships(s)
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1 Both XN extracts effectively protected PC12 cells against H2O2-induced cell damage by inhibiting release of lactate dehydrogenase, decreasing DNA damage, restoring mitochondrial membrane potential, and arresting abnormal apoptosis through upregulation of Bcl-2 and downregulation of Bax and caspase 3. Hydrogen Peroxide BCL2, apoptosis regulator Rattus norvegicus