Title : Hypotonic stress promotes ATP release, reactive oxygen species production and cell proliferation via TRPV4 activation in rheumatoid arthritis rat synovial fibroblasts.

Pub. Date : 2017 Apr 22

PMID : 28274876






2 Functional Relationships(s)
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1 These effects were almost abolished by calcium-free buffer and significantly inhibited by gadolinium (III) chloride (a mechanosensitive Ca2+ channel blocker) and ruthenium red (a transient receptor potential vanilloid 4 (TRPV4) blocker). Ruthenium Red transient receptor potential cation channel, subfamily V, member 4 Rattus norvegicus
2 These effects were almost abolished by calcium-free buffer and significantly inhibited by gadolinium (III) chloride (a mechanosensitive Ca2+ channel blocker) and ruthenium red (a transient receptor potential vanilloid 4 (TRPV4) blocker). Ruthenium Red transient receptor potential cation channel, subfamily V, member 4 Rattus norvegicus