Title : p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis.

Pub. Date : 2017 May

PMID : 28273432






3 Functional Relationships(s)
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1 We found induction of tumor suppressor protein, p53, and apoptosis with suppression of urokinase-type plasminogen activator (uPA) and the uPA receptor in AECs from the lungs of IPF patients, and in mice with bleomycin, cigarette smoke, silica, or sepsis-induced lung injury. Bleomycin plasminogen activator, urokinase Homo sapiens
2 We found induction of tumor suppressor protein, p53, and apoptosis with suppression of urokinase-type plasminogen activator (uPA) and the uPA receptor in AECs from the lungs of IPF patients, and in mice with bleomycin, cigarette smoke, silica, or sepsis-induced lung injury. Bleomycin plasminogen activator, urokinase Homo sapiens
3 We found induction of tumor suppressor protein, p53, and apoptosis with suppression of urokinase-type plasminogen activator (uPA) and the uPA receptor in AECs from the lungs of IPF patients, and in mice with bleomycin, cigarette smoke, silica, or sepsis-induced lung injury. Bleomycin plasminogen activator, urokinase Homo sapiens