Pub. Date : 2017 Feb
PMID : 28272690
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Licorice and its active compound glycyrrhizic acid ameliorates cisplatin-induced nephrotoxicity through inactivation of p53 by scavenging ROS and overexpression of p21 in human renal proximal tubular epithelial cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
2 | Cisplatin-induced apoptosis in renal cells is associated with reactive oxygen species (ROS)-mediated p53 activation. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
3 | Cisplatin-induced apoptosis in renal cells is associated with reactive oxygen species (ROS)-mediated p53 activation. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
4 | CONCLUSIONS: These results suggest that LE and GA ameliorate cisplatin-induced apoptosis through reduction of ROS-mediating p53 activation and promotion of p21 expression in HK-2 cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |