Pub. Date : 2017 Mar 8
PMID : 28272477
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Expression levels of both anti- and pro-apoptotic markers (Bcl-2 and Bax, respectively) decreased with increasing eugenol concentration, with no variation in their relative ratios. | Eugenol | BCL2 apoptosis regulator | Homo sapiens |
2 | Eugenol-treated MCF-7 cells overexpressing Bcl-2 exhibited results similar to those of MCF-7. | Eugenol | BCL2 apoptosis regulator | Homo sapiens |
3 | Our findings indicate that eugenol toxicity is non-apoptotic Bcl-2 independent, affecting mitochondrial function and plasma membrane integrity with no effect on migration or invasion. | Eugenol | BCL2 apoptosis regulator | Homo sapiens |