Title : Suppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate.

Pub. Date : 2017 Jul

PMID : 28265821






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, DN-AMPKalpha2 lentivirus and AMPKalpha2 siRNA were transfected into PA-treated L6 myotubes, and the decrease in SREBP-1c expression caused by insulin was blocked by AMPK inhibition independent of the phosphatidylinositol-4,5-biphosphate-3-kinase (PI3K)/AKT pathway. Palmitic Acid protein kinase, AMP-activated, alpha 2 catalytic subunit Mus musculus
2 Moreover, DN-AMPKalpha2 lentivirus and AMPKalpha2 siRNA were transfected into PA-treated L6 myotubes, and the decrease in SREBP-1c expression caused by insulin was blocked by AMPK inhibition independent of the phosphatidylinositol-4,5-biphosphate-3-kinase (PI3K)/AKT pathway. Palmitic Acid protein kinase, AMP-activated, alpha 2 catalytic subunit Mus musculus