Title : Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.

Pub. Date : 2017 Apr 28

PMID : 28258219






2 Functional Relationships(s)
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Protein Name
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1 Structures of binary complexes of PYCR1 with NADPH or proline determined at 1.9 A resolution provide insight into cofactor and substrate recognition. NADP pyrroline-5-carboxylate reductase 1 Homo sapiens
2 The 1.85 A resolution structure of a ternary complex containing NADPH and a P5C/proline analog provides a model of the Michaelis complex formed during hydride transfer. NADP pyrroline-5-carboxylate reductase 1 Homo sapiens