Title : Ameliorative effects of sildenafil and/or febuxostat on doxorubicin-induced nephrotoxicity in rats.

Pub. Date : 2017 Jun 15

PMID : 28257823






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1 Sildenafil and/or febuxostat administration with doxorubicin caused a significant decrease in nephrotoxicity markers and inflammatory mediators, restoration of normal values of oxidative stress biomarkers and hampering the expression of renal caspase-3. Sildenafil Citrate caspase 3 Rattus norvegicus