Title : BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.

Pub. Date : 2017 Feb 28

PMID : 28249162






1 Functional Relationships(s)
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Protein Name
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1 Mechanistically, BETi decreased Brd4 occupancy at the Cd274 locus without any change in Myc occupancy, resulting in transcriptional pausing and rapid loss of Cd274 mRNA production. beti bromodomain containing 4 Homo sapiens