Pub. Date : 2017 Feb 28
PMID : 28249154
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | beta-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | BHB inhibited NLRP3 inflammasome in S100A9 fibril-primed and urate crystal-activated macrophages, which serve to recruit inflammatory neutrophils in joints. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Mechanistically, BHB inhibited the NLRP3 inflammasome in neutrophils by reducing priming and assembly steps. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |