Title : The P2X7 receptor links mechanical strain to cytokine IL-6 up-regulation and release in neurons and astrocytes.

Pub. Date : 2017 May

PMID : 28244110






1 Functional Relationships(s)
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1 Intravitreal injection of P2X7 receptor antagonist BBG prevented the pressure-dependent rise in IL-6 mRNA and protein in the rat retina, while injection of P2X7 receptor agonist BzATP was sufficient to elevate IL-6 expression. coomassie Brilliant Blue purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus