Title : Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice.

Pub. Date : 2017 May

PMID : 28243714






3 Functional Relationships(s)
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1 Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Experiment 2 used 14 and 40 mg kg-1 day-1 nicotine treatment in alpha7 nAChR knockout (KO) and wildtype (WT) littermates tested 4 h after pump removal. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 CONCLUSIONS: The alpha7 nAChR may underlie nicotine withdrawal-induced deficits in target detection but is not required for response disinhibition deficits. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus