Pub. Date : 1987 Oct 6
PMID : 2823980
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cocaine stimulates adrenocorticotropin (ACTH) secretion through a corticotropin-releasing factor (CRF)-mediated mechanism. | Cocaine | corticotropin releasing hormone | Rattus norvegicus |
| 2 | The observation that this stimulatory effect was completely abolished by pretreatment with a corticotropin-releasing factor (CRF) antiserum, coupled with the lack of effect of cocaine on ACTH secretion by cultured pituitary cells, suggests that cocaine acts within the brain to release endogenous CRF. | Cocaine | corticotropin releasing hormone | Rattus norvegicus |