Pub. Date : 2017 May
PMID : 28238167
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment of 3xTg-AD mice with flavocoxid reduced: (1) learning and memory loss; (2) the increased eicosanoid production and the phosphorylation level of amyloid precursor protein (APP-pThr668), Abeta 1-42, p-tau (pThr181), pERK, and the activation of the NLRP3 inflammasome; (3) Abeta plaques; and (4) neuronal loss, compared to saline-treated animals. | flavocoxid | NLR family, pyrin domain containing 3 | Mus musculus |