Title : Trichostatin A attenuates ventilation-augmented epithelial-mesenchymal transition in mice with bleomycin-induced acute lung injury by suppressing the Akt pathway.

Pub. Date : 2017

PMID : 28234968






2 Functional Relationships(s)
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1 Trichostatin A attenuates ventilation-augmented epithelial-mesenchymal transition in mice with bleomycin-induced acute lung injury by suppressing the Akt pathway. Bleomycin thymoma viral proto-oncogene 1 Mus musculus
2 We hypothesized that trichostatin A (TSA), a HDAC inhibitor, can reduce MV-augmented bleomycin-induced EMT by inhibiting the HDAC4 and Akt pathways. Bleomycin thymoma viral proto-oncogene 1 Mus musculus