Title : A cytochemical study of the livers of rats treated with diethylnitrosamine/phenobarbital, with benzidine/phenobarbital, with phenobarbital, or with clofibrate.

Pub. Date : 1987 Oct 30

PMID : 2823419






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the DEN/PB and BZ/PB groups the parenchyma showed increases (even before PB treatment started) in G-6PD and in gamma-glutamyl transpeptidase (gamma-GT) and decreases in GSH. Phenobarbital gamma-glutamyltransferase 1 Rattus norvegicus
2 In the DEN/PB and BZ/PB groups the parenchyma showed increases (even before PB treatment started) in G-6PD and in gamma-glutamyl transpeptidase (gamma-GT) and decreases in GSH. Phenobarbital gamma-glutamyltransferase 1 Rattus norvegicus
3 Both initiators caused a high incidence of foci positive for G-6PD and for gamma-GT; nodules induced by DEN/PB were mainly positive for gamma-GT and showed an erratic response to the other parameters. Phenobarbital gamma-glutamyltransferase 1 Rattus norvegicus